Multiple myeloma is predominantly a disease of the elderly1

Median age at diagnosis 68 years2*

Elderly/frail patients have fewer treatment
options than younger patients3,4

*2014 EU data

Patients >65 years of age have worse survival rates than younger patients1

Characteristics commonly found in elderly patients make
treatment di cult1,4-6

Common symptoms can all be attributed to other etiologies in elderly patients

Difficulty of diagnosis in elderly patients3

50% of patients need 3 GP visits before diagnosis

Average delay in diagnosis: 6 MONTHS

There is an unmet medical need in this di cult-to-treat patient population

    1. National Cancer Institute. Available at:;
    2. Raab MS, et al. Br J Haematol 2016;175(1):66 76;
    3. Willan J, et al. Clin Interv Aging 2016;11:423–35;
    4. Palumbo A, et al. Blood 2015;125:2068–74;
    5. Fried J, et al. J Gerontol A Biol Sci Med Sci 2004;59:255–63;
    6. NCCN Guidelines: Multiple Myeloma Version 4.2022. Available at:;
    7. Chim CS, et al. Leukemia 2018;32:252–62;
    8. Egan JB, et al. Blood 2012;120:1060–6;
    9. Hutchins LF, et al. N Engl J Med 1999;341:2061–7;
    10. Baijal P & Periyakoil V. Cancer J 2014;20:358–66.