Allergic bronchopulmonary candidiasis: A review of the literature and a case report
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Allergic bronchopulmonary candidiasis (ABPC) is an uncommon clinical syndrome associated with immune hypersensitivity to Candida species. The case presentation describes a 58-year-old man with acute respiratory failure and bilateral lung infiltrates. Due to high inflammatory markers and a chest X-ray indicating lung infiltration, he was initially treated for pneumonia with combined antibiotics. Despite comprehensive treatment at the ICU, the patient’s clinical status deteriorated rapidly, and further investigations provided a rare diagnosis of ABPC. After several days of combined corticosteroid and antifungal therapy, we observed rapid clinical improvement and subsequent resolution of the pulmonary infiltrates. Key point: In conclusion, our case underlines that ABPC can be a life-threatening disease that can present with bilateral lung infiltrates and severe respiratory insufficiency. Precise diagnosis and early corticosteroid and antifungal therapy initiation appears to be the treatment of choice, as prompt clinical improvement is expected. The main goals of ABPC treatment are immunosuppression and eradication of the causative agent.
