Renal impairment is a common complication in patients with multiple myeloma

Patients with renal impairment are o en excluded from or underrepresented in clinical trials1

...and it forms a core part of the CRAB criteria used to diagnose multiple myeloma2,3

Renal impairment adversely affects survival

The median survival of patients with renal impairment is approximately half that of patients without renal impairment4

There are multiple contributors to renal impairment2

Depth of renal impairment at diagnosis is predictive of poor prognosis6

eGFR (mL/min/1.73m²)

    1. Richardson PG, et al. Blood Cancer J. 2018; 8(11)109;
    2. Faiman B et al. Clin J Oncol Nurs 2017;21(5 Suppl):19–36;
    3. Rajkumar SV, et al. Lancet Oncol. 2014;15:e538–48;
    4. Eleutherakis-Papaiakovou V, et al. Leuk Lymphoma 2007;48:337-41;
    5. Dimopoulos AM, et al. Leukemia. 2008;22:1485–93;
    6. Uttervall K et al. PLoS One. 2014;9;e101819

MAT-AE-2300647-V1-Nov-23