Type 2 inflammation underlies multiple chronic inflammatory diseases, which can manifest as individual or coexisting diseases involving various epithelial tissues in different organ systems (eg, skin, nose, lungs, esophagus).

IL-4 and IL-13 are key and central drivers of Type 2 pathophysiology and the various clinical manifestations observed. Prevalence of Type 2 Inflammation in Various Diseases, ~80% of CRSwNP1 patients is a type 2 inflammation.

MAT-BH-2300374/V1/JUNE 2023