The role of Epithelial Barrier Components in AD, insights and implications
This video provides insights into the key components and functions of the epithelial barriers in the skin. It highlights how barrier dysfunction plays a central role in the pathology of atopic dermatitis and emphasizes the importance of transepidermal water loss as a marker of barrier integrity and disease severity.
Long Term Impact of AD and the Potential benefits of early intervention
This video explores the long-term, multi-dimensional burden of moderate-to-severe atopic dermatitis, highlighting its impact beyond the skin. It emphasizes the importance of early intervention targeting type 2 inflammation to alter the disease course and prevent long-term comorbidities.
IL4 and IL13 important role in Chronic Itch
Discover the science beyond histamine: This video reveals how chronic itch in atopic dermatitis is predominantly mediated through non-histaminergic pathways. Learn how IL-4 and IL-13, key drivers of type 2 inflammation, create a critical intersection between inflammatory cascades and neural itch signaling. Understand the clinical implications of targeting these dual cytokines to simultaneously address both inflammation and the persistent itch cycle that significantly impacts patient quality of life.
The Cumulative Disease Burden of AD in Adult Patients
This video highlights that the burden of atopic dermatitis in adults extends beyond skin symptoms, encompassing a broad spectrum of atopic and non-atopic comorbidities. These related conditions have a major impact on patient care, clinical decisions, and overall quality of life.