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Flu and Respiratory Disease

In patients with respiratory disease

Flu Can Have A Devastating Impact1

Your patients with chronic respiratory conditions are at increased risk for dangerous complications when diagnosed with influenza2-5

In a study of the correlation between influenza and pneumonia, participants with symptomatic influenza had6:

~8x (95% CI: 4.8-14.5)
increased risk of developing pneumonia within a week following influenza infection

3234 children aged 0-14 years old were enrolled in this Nicaraguan study.6,a

Study limitations: Generalizability to US children may be limited. Given pneumonia is a rare outcome, the categorization by subtype resulted in fewer cases per strata, which may limit statistical power.6

The American Lung Association urges eligible individuals aged 6 months and older to get their annual flu shot7

Protecting against influenza can help reduce the risk of pneumonia and can help keep your patients out of the hospital.2,4,8

  1. Estimated flu-related illnesses, medical visits, hospitalizations, and deaths in the United States — 2019–2020 flu season. Centers for Disease Control and Prevention. October 1, 2021. Accessed November 11, 2021. https://www.cdc.gov/flu/about/burden/2019-2020.html
  2. Flu & people with asthma. Centers for Disease Control and Prevention. August 26, 2021. Accessed November 11, 2021. https://www.cdc.gov/flu/highrisk/asthma.htm
  3. FluView. Laboratory-confirmed influenza hospitalizations. Centers for Disease Control and Prevention. Accessed November 11, 2021. https://gis.cdc.gov/grasp/fluview/FluHospChars.html
  4. Kalil AC, Thomas PG. lnfluenza virus-related critical illness: pathophysiology and epidemiology.Crit Care.2019;23:258. doi:10.1186/s13054-019-2539-x
  5. MacNee W. ABC of chronic obstructive pulmonary disease: pathology, pathogenesis, and pathophysiology.BMJ.2006;332:1202-1204.
  6. Kubale J, Kuan G, Gresh L, et al. Individual-level association of influenza infection with subsequent pneumonia: a case-control and prospective cohort study. Clin Infect Dis. 2020. doi:10.1093/cid/ciaa1053
  7. Top health organizations urge flu and COVID-19 vaccines to protect vulnerable, reduce burden on hospitals. American Heart Association. September 27, 2021. Accessed November 11, 2021. https://newsroom.heart.org/news/top-health-organizations-urge-flu-and-covid-19-vaccines-to-protect-vulnerable-reduce-burden-on-hospitals
  8. Grohskopf LA, Alyanak E, Ferdinands JM, et al. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, United States, 2021–22 influenza season. MMWR. 2021;70(5):1-28. doi:10.15585/mmwr.rr7005a1
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MAT-BH-2300264 – V1 – Feb 2024