This educational video examines the pathophysiological mechanisms underlying mucus plug formation in asthma and explores their clinical significance in airway obstruction. The presentation addresses how mucus plugging contributes to disease burden and persistent symptoms in asthmatic patients. Healthcare professionals will learn about the cellular and molecular processes involved in mucus hypersecretion and their impact on patient outcomes.

This video presents results from the Phase 4 VESTIGE trial, demonstrating how dupilumab improves airway structure and function in severe type 2 asthma. Using breakthrough Functional Respiratory Imaging technology, the study reveals structural improvements that conventional lung function tests may not detect.