| ENHANCED ALGORITHMS | ||
| STRATEGIES | ADVANTAGES | LIMITATIONS |
| HCL systems incorporating heart rate, accelerometry along with energy expenditure and galvanic skin response | For detection of physical activity and improvements in glycemic outcomes | These algorithms reactive and remain subject to the slower PK of subcutaneous insulin absorption |
| Machine learning for personalization of CL systems | Recognizes habitual pattern of imminent exercises and trigger CL systems | Potential risks associated with insulin dosing determined upon the basis of the probability of an event occurring |
MAT-BH-2200900/V1/Nov 2022