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T1D is an autoimmune disease whereby autoreactive T-cells drive progressive beta-cell damage and destruction, ultimately leading to insulin deficiency, dysglycemia, and hyperglycemia.
Staging of autoimmune T1D allows us to track the progressive nature of the disease, from autoimmunity through to insulin dependence.
Monitoring people with early-stage autoimmune T1D may reduce the risk of serious complications, such as DKA.
Why and Who: an overview of the key considerations and decisions that inform screening people for islet autoantibodies.
The burden associated with a diagnosis of autoimmune T1D can be wide-ranging. This video describes the impact of diagnosis on an individual and their family.
Phase 2 trial of neoadjuvant docetaxel, oxaliplatin, and S-1 for clinical stage III gastric or esophagogastric junction adenocarcinoma Kurokawa Y, et al. Ann Gastroenterol Surg. 2022 Oct 18;7(2):247-254.