Science at Sanofi

This evidence-based 3.17-minute video explores how uncontrolled atopic dermatitis creates cumulative disease burden beyond visible skin manifestations. Discover the hidden burden—psychological, social, and systemic impacts often overlooked—and the long-term implications of chronic inflammation. Learn to recognize progression patterns and the critical importance of early intervention strategies.

This educational video examines the pathophysiological mechanisms underlying mucus plug formation in asthma and explores their clinical significance in airway obstruction. The presentation addresses how mucus plugging contributes to disease burden and persistent symptoms in asthmatic patients. Healthcare professionals will learn about the cellular and molecular processes involved in mucus hypersecretion and their impact on patient outcomes.

This poster presentation evaluates the efficacy of dupilumab in treating eosinophilic esophagitis (EoE) in patients weighing ≥15 kg at baseline from the Phase 3 KIDS study.

Study Overview: The analysis examines dupilumab efficacy stratified by previous treatment history, including:

- Prior or current use of swallowed topical corticosteroids (STCs) 
- Concomitant proton pump inhibitor (PPI) treatment 
- History of food elimination diet

This educational video examines the prevalence of moderate and severe atopic dermatitis in children, presenting data that describes the significant disease burden and its impact on both pediatric patients and their families. The content explores current challenges in achieving optimal disease control in children with moderate and severe atopic dermatitis, providing healthcare professionals with evidence-based insights into the clinical management complexities of this patient population.

The soundbite recording captures Dr. Paller's discussion on factors that contribute to the development of atopic comorbidities in patients with atopic dermatitis. The presentation examines the relationship between AD and associated atopic conditions.

The soundbite recording captures Dr. Paller's discussion examining whether early therapeutic intervention can influence the natural course of atopic dermatitis. The presentation explores the potential for timely treatment approaches to modify disease trajectory.

The soundbite recording captures Dr. Simpson's discussion exploring the concept of remission in atopic dermatitis, examining what remission could mean in the context of AD management and patient outcomes.

The soundbite recording captures Dr. Paller's presentation examining the relationship between age of disease onset and AD persistence. The discussion explores how earlier onset of atopic dermatitis may influence disease trajectory and long-term outcomes in patients.

The soundbite recording captures Dr. Ramien's discussion of disease modification concepts in atopic dermatitis, exploring current understanding and approaches to altering disease progression.

This educational video features Dr. Eric Simpson's presentation on the Impact of Advanced Systemic Therapies on Disease Control in AD