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Complete the circle of protection with DTP & IPV booster vaccines

Is your child missing the school entry booster! Complete the circle of protection with DTP & IPV Booster Vaccines

Aid the parents with the armor of knowledge! In this issue we speak about the DTP & IPV booster and its importance. Through this input, help the parents know more about this vaccine so that their child does not miss on this important school entry booster!

What is DTP & IPV vaccine?

DTP & IPV booster vaccines are given to protect your child against infections caused by1

  • Diphtheria
  • Tetanus
  • Pertussis
  • Poliovirus

The vaccine causes the body to produce a shield against these diseases1

How serious are these diseases?

These diseases can cause breathing difficulties, heart problems, muscle spasms and inability to walk, paralysis, and even death1

Why do we need boosters?

  • High disease transmission and waning of immunity against the disease among school entry children3,4
  • Once vaccinated the child is protected for long term5
  • New ACVIP guideline recommends the DTP & IPV booster shot in school entry children5

DTP & IPV as school entry boosters

  • Booster can be given independent to the primary vaccine(s) or previous vaccination schedule6
  • Maintains high immunity from early childhood up until the adolescent booster7 
  • Is well-tolerated in toddlers8

References

  1. Diphtheria, tetanus, pertussis and polio vaccine [Internet] [Updated Mar 01, 2022]. Available at: https://www.mayoclinic.org/drugs-supplements/diphtheria-tetanus-acellular-pertussis-polio-vaccine-intramuscular-route/description/drg20071983#:~:text=Diphtheria%2C%20tetanus%2C%20and%20acellular%20pertussis,whooping%20cough)%2C%20and%20poliovirus. Accessed on May 26, 2022.
  2. Prevention [Internet] [Updated May 26, 2020]. Available at: https://www.cdc.gov/diphtheria/about/prevention.html. Accessed on May 26, 2022.
  3. Klein NP, Bartlett J, Rowhani-Rahbar A, Fireman B, Baxter R. Waning protection after fifth dose of acellular pertussis vaccine in children. N Engl J Med. 2012 Sep 13;367(11):1012-9. Available at: https://www.nejm.org/doi/pdf/10.1056/NEJMoa1200850?articleTools=true.
  4. Gao H, Lau EH, Cowling BJ. Waning immunity after receipt of pertussis, diphtheria, tetanus, and polio-related vaccines: A systematic review and meta-analysis. J Infect Dis. 2022 Feb 15;225(4):557-566. Available at: https://academic.oup.com/jid/arrtcle-abstract/225/4/557/6372879?redirectedFrom=fulltext&login=false.
  5. Kasi SG, Shivananda S, Marathe S, Chatterjee K, Agarwalla S, Dhir SK, et al. Indian Academy of Pediatrics (IAP) Advisory Committee on vaccines and immunization practices (ACVIP): Recommended immunization schedule (2020–21) and update on immunization for children aged 0 through 18 years. Indian Pediatrics. 2021 Jan;58(1):44-53. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840391/pdf/13312_2021_Article_2096.pdf.
  6. Mallet E, Matisse N, Mathieu N, Langue J, Boisnard F, Soubeyrand B; Pentavac Study Group. Antibody persistence against diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type b (Hib) in 5-6-year-old children after primary vaccination and first booster with a pentavalent combined acellular pertussis vaccine: immunogenicity and tolerance of a tetravalent combined acellular pertussis vaccine given as a second booster. Vaccine. 2004 Mar 29;22(11-12):1415-22. Available at: https://www.sciencedirect.com/science/article/pii/S0264410X03007734?via%3Dihub.
  7. John T, Voysey M, Yu L, McCarthy N, Baudin M, Richard P, et al. Immunogenicity of a low-dose diphtheria, tetanus and acellular pertussis combination vaccine with either inactivated or oral polio vaccine compared to standard-dose diphtheria, tetanus, acellular pertussis when used as a pre-school booster in UK children: A 5-year follow-up of a randomised controlled study. Vaccine. 2015 Aug 26;33(36):4579-85. Available at: https://www.sciencedirect.com/science/article/pii/S0264410X15009226?via%3Dihub.
  8. Ferrera G, Cuccia M, Mereu G, Icardi G, Bona G, Esposito S, et al. Booster vaccination of pre-school children with reduced-antigen-content diphtheria-tetanus-acellular pertussis-inactivated poliovirus vaccine co-administered with measles-mumps-rubella-varicella vaccine: A randomized, controlled trial in children primed according to a 2 + 1 schedule ni infancy. Hum Vaccin Immunother. 2012 Mar;8(3):355-62. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC3426082/pdf/hvi-8-355.pdf.

 

MAT-IN-2202341-10/2022