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Do antibiotics cause obesity through long-term alterations in the gut microbiome? A review of current evidence

Current evidence on the association between antibiotics and the subsequent development of obesity through modulation of the gut microbiome has been summarized. Particular emphasis is given on:

  1. Animal and human studies and their limitations
  2. The reservoir of antibiotics in animal feed, emerging antibiotic resistance, gut dysbiosis, and obesity
  3. The role of infections, specifically viral infections, as a cause of obesity
  4. The potential therapeutic approaches other than antibiotics to modulate gut microbiome
MAT-IN-2201504 v1.0 06/22