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Understanding Autoimmune T1D & The Value of Early Detection

Author : Sanofi Editorial Team
Reading Time: 1 min

Autoimmune Type 1 Diabetes (T1D) can be detected through islet autoantibody testing years before symptoms appear.1-2 The video here explains how the condition progresses silently through presymptomatic stages, with beta cell destruction occurring long before symptom onset and clinical diagnosis.4-8

In 4 minutes, learn how early detection through systematic screening can reduce diabetic ketoacidosis (DKA) rates by up to 90%, how screening can reduce risk of acute complications, and how early detection of T1D can improve both short and long-term outcomes for people who develop the condition.9-11

The scientific literature is clear: identifying autoimmune T1D in its earliest stages provides critical time for early diagnosis, intervention and preparation.1-3
Early detection can transform life for those who develop autoimmune T1D and their families. Screen today for better outcomes tomorrow.

Early Detection of Autoimmune Type 1 Diabetes (på dansk)

Early Detection of Autoimmune Type 1 Diabetes (in English)

Produced by Sanofi North Europe, based on cited literature.

  1. Insel RA, et al. Diabetes Care. 2015;38(10):1964-1974.

  2. Ziegler AG, et al. JAMA. 2013;309(23):2473-2479.

  3. Haller MJ, Bell KJ, Besser REJ et al. (2024) ISPAD Consensus Guidelines, Horm Res Paediatr 1-30

  4. Bonifacio E, et al. Diabetologia. 2017;60(10):1967-1976.

  5. Krischer JP, et al. Diabetologia. 2015;58(6):1310-1318.

  6. Jacobsen LM, et al. Diabetes Care. 2018;41(9):1906-1913.

  7. Dayan CM, Besser REJ, Oram RA et al. (2021) Science 373, pp506–10 2

  8. Ozen G, Zanfardino A, Confetto S et al. (2020) Int J Endocrinol. 2020,2630827

  9. Wherrett DK, et al. Diabetes Care. 2018;41(8):1669-1680.

  10. Steck AK, et al. Diabetes Care. 2019;42(11):2027-2033.

  11. Ziegler AG, et al. JAMA. 2020;323(4):339-351.

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MAT-BE-2501137-v1.0-25SEP2025