Quality of life and symptom measurement in COPD Patients

The SGRQ measures the qualitative impact of COPD^1,a

Some domains evaluated by the SGRQ include²:

*Such as walking upstairs or getting dressed.

E-RS-COPD assess COPD symptoms^b

Some domains evaluated by the E-RS-COPD include²:

This is not an exhaustive list of items evaluated by the SGRQ and E-RS-COPD.

^a The SGRQ is a 50-item questionnaire designed to measure the qualitative impact of COPD on overall health , daily life, and perceived well-being. Higher scores mean greater disease severity. ^1
b E-RS-COPD is an 11-item patient-reported derivative tool that measures the effect of treatment on respiratory symptom severity in patients with stable COPD . Higher scores mean greater disease severity. ³

COPD, chronic obstructive pulmonary disease; E-RS-COPD, Evaluating Respiratory Symptoms in COPD; QoL, quality of life; SGRQ, St George’s Respiratory Questionnaire

^* Type 2 inflammation defined as elevated biomarker in COPD (Blood EOS ≥300 cells/μL or ≥2%, or Sputum EOS ≥ 3%)

References

1. Jones PW. St George’s Respiratory Questionnaire: MCID. COPD. 2005 Mar;2(1):75-79.

2. Evidera website. EXACT and E-RS:COPD content. Accessed [February 9, 2024]. https://www.evidera.com/what-we-do/patient-centered-research/coa-instrument-management-services/exact-program/ exact-content/

3. Leidy NK, Bushnell DM, Thach C, Hache C, Gutzwiller FS. Interpreting Evaluating Respiratory Symptoms in COPD diary scores in clinical trials: terminology, methods, and recommendations. Chronic Obstr Pulm Dis. 2022;9(4):576-590.