CRSwNP - Kronisk rhinosinusitt med nesepolypper

This Italian monocentric study (De Corso et al., 2022) evaluated the real-life effectiveness of dupilumab over the first year of treatment of severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) (N=57).² The results from this real-life observational study reinforces the efficacy of dupilumab demonstrated in the SINUS-24 and SINUS-52 randomized clinical trials and both the study design and results are consistent with the approved SmPC.^1,2,3

Loss of sense of smell is a common symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), but its impact is often underestimated. Learn how olfactory dysfunction affects patient’s quality of life and explore the underlying mechanisms driving smell loss in CRSwNP.

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) generally have a high symptom burden and poor health-related quality of life (QoL), often requiring recurring systemic corticosteroid use and repeated sinus surgery.

The results from the DUPIREAL real-world study reinforce the efficacy of dupilumab demonstrated in the SINUS-24 and SINUS-52 randomized clinical trials and are consistent with the approved SmPC.^1,2,3,4 DUPIREAL is the largest long-term real-world study (n=926) evaluating the effectiveness of dupilumab, including treatment response, disease control and remission, in severe uncontrolled CRSwNP over 2 years.^3,4

First ever direct Head-to-Head Comparison of Dupilumab vs Omalizumab in Patients with Severe CRSwNP and Coexisting Asthma.

Polyp Gossip is a video podcast dedicated to exploring Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). Hosted by two globally recognized rhinologists. The show delves into trending topics, latest advancements, and patient experiences. Each episode features esteemed guests, including experts and patients, offering valuable insights into the evolving world of CRSwNP.

In this episode of Polyp Gossip, we uncover the truth about steroids in CRSwNP—exploring their benefits, limitations, and impact on long-term management. Our experts cut through the myths to reveal what every patient and clinician should really know.

In this episode of Polyp Gossip, we delve into the everyday impact of CRSwNP, examining how breathing difficulties, loss of smell, and emotional well-being are deeply interconnected. Join leading experts and patients as they share insights and experiences on living with this condition. Their perspectives shed light on the human side of CRSwNP, reminding us that every symptom affects far more than health.

Can remission become the new benchmark in CRSwNP care? In this episode, our expert panel explores the evolving treatment landscape and what "remission" truly means for patients and clinicians. Join us as we look ahead to a future beyond symptom control - where long-term outcomes and deeper disease understanding could transform the way we define treatment success.

What links CRSwNP, asthma, and other comorbidities? In this episode, our experts unpack the unified airways concept and why it’s key to understanding Type 2 inflammation and optimizing patient care. Our experts discuss integrated care approaches and what they mean for clinical practice.

In this episode of Polyp Gossip, we explore the importance of a multidisciplinary approach in managing Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). Join leading experts from rhinology and pulmonology as they discuss how collaboration across specialties can improve patient outcomes and optimize care pathways.

In this episode of Polyp Gossip, we explore the power of personalized care in CRSwNP. From symptoms to patient profiles, our experts discuss how tailored treatment strategies can lead to better outcomes and improved quality of life. Tune in to discover what "finding what works best for you" really means in today's evolving care landscape.

In this episode we explore the critical decision of whether surgery is the right choice for CRSwNP patients. Leading experts discuss the factors influencing surgical vs. medical management, patient considerations, and the latest advancements in treatment. Tune in for an in-depth look at this big decision in CRSwNP care!