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Clinician’s Guide to cGVHD

Despite advances in transplantation techniques and immunosuppressive therapies, cGVHD remains a leading cause of non-relapse morbidity and mortality post-HSCT. Managing cGVHD requires an understanding of its heterogeneous presentation, pathophysiology, diagnostic criteria, and treatment options. This section provides curated articles on these topics.

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aGvHD, acute graft-versus-host disease; alloHCT, allogeneic hematopoietic cell transplant; cGvHD, chronic graft-versus-host disease; GvHD, graft-versus-host disease; HCT, hematopoietic stem cell transplant; HLA, human leukocyte antigen; vs, versus.

MAT-BE-2500625, v1.0, May 2025