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Clinical presentation and pathophysiology of Prurigo Nodularis (PN)

Clinical presentation and pathophysiology of Prurigo Nodularis (PN)

Explore the clinical presentation and pathophysiology of Prurigo Nodularis (PN), including its systemic inflammation, itching-scratching cycle, and effects on quality of life. Learn about the underlying mechanisms and treatment options for this chronic skin condition.

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Glycaemic Targets and Vascular Complications in Type 2 Diabetes: What Are the Thresholds?<sup>1</sup>

Glycaemic Targets and Vascular Complications in Type 2 Diabetes: What Are the Thresholds?

Summary of Zoungas S, et al. Diabetologia. 2012;55:636–643.

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Approach for patients with coronary artery disease (CAD): focus on LDL-C control

Approach for patients with coronary artery disease (CAD): focus on LDL-C control

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When to Initiate Basal Insulin?

When to Initiate Basal Insulin?

Practical Guidance based on the 2022 ADA/EASD Guidelines.

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Approach for patients with peripheral artery disease (PAD) + T2DM: focus on LDL-C control

Approach for patients with peripheral artery disease (PAD) + T2DM: focus on LDL-C control

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Cardiovascular diseases (CVDs) are the leading cause of death globally<sup>1</sup>

Cardiovascular diseases (CVDs) are the leading cause of death globally

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What is PRALUENT<sup>®</sup>(alirocumab)?

What is PRALUENT®(alirocumab)?

PRALUENT®: a PCSK9i that ticks all the boxes1–4

 

PRALUENT is a PCSK9i that reduces the levels of LDL-C in the blood.2 It is a fully human IgG1 monoclonal antibody that works by inhibiting the binding of PCSK9 to LDL- receptors. As a result, PRALUENT increases the number of LDL-receptors available to clear LDL, thereby lowering LDL-C levels.2 Elevated LDL-C levels have been significantly associated with cardiovascular disease such as heart attacks and strokes.1

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Signs and symptoms of aTTP

Signs and symptoms of aTTP

Know the signs and symptoms of acquired TTP (aTTP).

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What is TTP? A rare, life-threatening medical emergency

What is TTP? A rare, life-threatening medical emergency

Early diagnosis and treatment of Thrombotic thrombocytopenic purpura (TTP) can help prevent the high risk of early deaths.

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When to suspect TTP?

When to suspect TTP?

TTP is rare and presents similarly to other thrombotic microangiopathies (TMAs), making it difficult to diagnose.

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Why is Glycaemic Control in Type 2 Diabetes Still a Challenge?

Why is Glycaemic Control in Type 2 Diabetes Still a Challenge?

Summary of Aschner P, et al. Diabetologia. 2020;63(4):711-721.

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How Does Glycaemic Control Impact Complications in Type 2 Diabetes?

How Does Glycaemic Control Impact Complications in Type 2 Diabetes?

Summary of The UK Prospective Diabetes Study (UKPDS).

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