Recognizing the Urgency to proactively plan a switch: Managing Timely Insulin Transitions for Continuity of Care
Learn why timely insulin transitions are critical for patient safety and continuity of care. Act early to avoid gaps and risks.
The Urgency to proactively plan a switch: A Proactive Approach to Managing Insulin Discontinuation
The withdrawal and discontinuation of insulin products from the market can notably disrupt established treatment plans, potentially causing stress in people with diabetes using insulin and healthcare professionals (HCPs).1,2 Despite advance notice of discontinuation, many patients continue using insulins that will soon be unavailable, and new patients are still initiated on them.2 This creates an urgent need for HCPs to develop effective strategies for managing these transitions.1
This article highlights the importance of proactive insulin transition planning and offers practical guidance to help HCPs manage these changes while maintaining quality care.
The Impact of Insulin Discontinuation
The discontinuation of insulin products presents unique challenges in diabetes management. Different insulin formulations often require different dosing regimens, necessitating careful titration and monitoring when switching between products.1 For insulin products not available in a disposable pen/device, HCPs may need to educate patients on how to load cartridges into reusable pen devices, adding another layer of complexity to the transition process.1
Additionally, issues of access and affordability may complicate transitions. Patients may face barriers when switching to alternative insulins, including insurance coverage limitations, higher out-of-pocket costs, or availability constraints.3,4 These challenges underscore the importance of proactive planning and communication when insulin discontinuations occur.
Despite early announcements, many providers postpone transition planning, assuming that existing stock will last longer than it typically does. Some new patients are still being prescribed insulins that will soon be discontinued, resulting in avoidable transition challenges.1
The Challenges in Insulin Transitions
Transitioning patients to alternative insulin products presents several challenges1:
Practical Strategies for Effective Insulin Transitions
1. Early Identification and Communication
Proactively identify all patients using insulins that are soon to be discontinued. Prioritize based on glycemic control, comorbidities, and social support.1
2. Selecting Appropriate Alternatives
When selecting alternative insulin products, consider:
- Pharmacokinetic profiles1
- Patient specific factors and preference1
- Access, affordability, and insurance coverage3,4,6
- Availability of suitable delivery devices and patient’s ability to use them effectively1
3. Conducting Effective Transition Discussions
To increase confidence when discussing transitions with patients:
Frame the Conversation Positively |
Address Concerns Directly |
Provide Clear Information |
Create a Structured Plan |
| Present the transition as an opportunity.1 | Communicate any changes to all involved in the care of the person with diabetes, providing reassurance about continued support.1 | Explain why the transition is necessary and the potential benefits of alternative options.1 | Outline structured plan, including dosage, follow-up, and monitoring expectations.1 |
Implementing Effective Transition Strategies
Healthcare teams can benefit from developing standardized protocols for insulin transitions, including:
- Maintain a registry of patients using insulins that are soon to be discontinued.1
- Provide comprehensive education on alternative insulin products, including proper handling and methods of administration.1
- Monitor blood glucose regularly after any change in insulin to ensure appropriate dosing and glycemic control.1
For insulin products not available in a disposable pen/device, HCP may need to educate patients on how to load cartridges into reusable pen devices.1 This education should occur both at the point of dispensing and during administration.
Reducing the Burden Through Effective Communication
Patients may be hesitant about switching insulin products due to concerns about effectiveness, side effects, or changes to their routine. HCPs can help address these concerns by:1,2
- Acknowledging patient concerns and validating their feelings about changing their established regimen
- Explaining the reason for the switch and the selection process for the alternative insulin
- Providing clear instructions on the alternative insulin product and dosing
- Discussing proper use, handling, and method of administration
- Ensuring the patient understands storage requirements and costs
- Scheduling appropriate follow-up to monitor response to the new insulin
By approaching these conversations with confidence, preparedness, and empathy, HCPs can transform a challenging situation of insulin transitions into a productive patient engagement journey.
Conclusion
Proactive planning, effective communication, and system-level readiness not only ensures patient safety from dosing errors, side effects, and treatment disruptions but also reduces the burden on healthcare systems.
The key to a smooth transition lies in recognizing the urgency today—rather than delaying these essential conversations until stock depletion creates crisis conditions. Taking action early may help patients successfully navigate necessary changes to their diabetes management regimens.
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Australian Commission on Safety and Quality in Health Care. (2025). Guidance - Discontinuation of insulin products: Strategies and safety considerations. https://www.act.gov.au/__data/assets/pdf_file/0018/2831013/Insulinsupply- changes-Information-for-clinicians.pdf (Accessed on June 12, 2025)
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Feldman R. Leading with the trailing edge: facilitating patient choice for insulin products. J Law Biosci. 2023;10(2):lsad033. Published 2023 Dec 12. doi:10.1093/jlb/lsad033
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Cefalu WT, Dawes DE, Gavlak G, et al. Insulin Access and Affordability Working Group: Conclusions and Recommendations [published correction appears in Diabetes Care. 2018 Aug;41(8):1831. doi: 10.2337/dc18- er08.]. Diabetes Care. 2018;41(6):1299-1311. doi:10.2337/dci18-0019
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Luo J, Avorn J, Kesselheim AS. Trends in Medicaid Reimbursements for Insulin From 1991 Through 2014 [published correction appears in JAMA Intern Med. 2016 Mar;176(3):417. doi: 10.1001/jamainternmed.2015.8190.]. JAMA Intern Med. 2015;175(10):1681-1686. doi:10.1001/jamainternmed.2015.4338
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Park K, Jeong AE, Guenther-Gleason E, Jain SH. Impact of switching analogue insulin to human insulin in diabetes. Am J Manag Care. 2019;25(10 Spec No.):88173. Published 2019 Sep 1.
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Luo J, Kesselheim AS, Sarpatwari A. Insulin access and affordability in the USA: anticipating the first interchangeable insulin product. Lancet Diabetes Endocrinol. 2020;8(5):360-362. doi:10.1016/S2213- 8587(20)30105-4