Preventive Cardiology: Key Insights from Professor Michal Vrablik

Below is a summary of a recent interview with Professor Michal Vrablik. The reading time is approximately 5 minutes.
Key Takeaways
- Preventive cardiology focuses on distinguishing between severe and less severe coronary atherosclerosis.
- A new scoring system helps identify individuals with higher plaque burden and more severe stenosis.
- Premature death from acute heart attacks remains a significant threat, with a high mortality rate.
- Atherosclerosis is a systemic disease affecting multiple vascular beds, including cerebrovascular and peripheral arteries.
- Screening for risk factors like arterial hypertension and dyslipidemia, especially elevated LDL-C, is crucial.
- Systematic screening should be done at every opportunity, particularly for those with a positive family history or at-risk age.
- Atherosclerosis develops due to a cluster of risk factors acting simultaneously, necessitating aggressive treatment.
- Modern imaging methods like CT angiography and calcium scoring improve risk estimates and early identification of at-risk individuals.
Watch the video here or read the summary below:

In a recent interview, Professor Michal Vrablik, who works at the General University Hospital and First Faculty of Medicine of Charles University in Prague, shared his expertise in preventive cardiology. He explained that this field focuses on distinguishing between severe and less severe coronary atherosclerosis. A newly developed scoring system helps identify individuals with a higher plaque burden and more severe stenosis, which is crucial for targeted prevention strategies.
Professor Vrablik emphasized that premature death from acute heart attacks remains a major threat, with a significant mortality rate. He noted that atherosclerosis is a systemic disease that affects multiple vascular beds, including cerebrovascular and peripheral arteries, leading to various severe consequences if left untreated.
To prevent the first cardiovascular event, thorough screening of risk factors is essential. Professor Vrablik highlighted the importance of identifying common risk factors such as arterial hypertension and dyslipidemia, particularly elevated levels of LDL-Cholesterol (LDL-C). He stressed that lipid screening should be performed at every opportunity, especially for individuals with a positive family history or those at an age where risk increases.
Atherosclerosis develops due to a cluster of risk factors acting simultaneously on the vessel walls. Therefore, it is crucial to search for and treat these metabolic and cardiovascular abnormalities aggressively. This is particularly important for patients with insulin resistance, metabolic syndrome, and type 2 diabetes, who are at the highest risk of atherosclerotic complications.
Professor Vrablik also pointed out that atherosclerosis is often asymptomatic, making systematic screening vital for early detection. Modern imaging methods, such as CT angiography and calcium scoring of coronary arteries, enhance the precision of risk estimates and help identify at-risk individuals before atherosclerosis fully develops.
In conclusion, Professor Vrablik's insights highlight the importance of preventive cardiology, systematic screening, and aggressive treatment of risk factors to manage and reduce the burden of cardiovascular diseases effectively.